Life in the Vascular Wall
1 - 2 December 2024
Aim
This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD Students from NorDoc member faculties. All other participants must pay the course fee.
Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from NorDoc member faculties. After the enrollment deadline, available seats will be allocated to applicants on the waiting list.
Learning Objectives
A student who has met the objectives of the course will be able to:
1. Demonstrate a broad overview of vascular function.
2. Put into perspective their own research topic in the context of broad vascular function.
3. Obtain an overview of several cells types in the vascular wall, including smooth muscle, endothelial, perivascular adipose cells.
4. Understand the importance of the spatial and temporal control of calcium for vascular function.
5. Analyse topical pro and con arguments in the field of vascular physiology, and demonstrate an ability to present these arguments in the form of a debate.
6. Consider the implications of arterial remodeling in the context of vascular disease.
Content
This course will cover basic vascular function from a broad physiological perspective through to highlighting the importance of multiple cell types found in the vascular wall. The programme will take the student from an overview of the whole vascular network, showing how it meets the demands of the body, through to focused lectures on ion channels and the spatial and temporal control of calcium in regulating vascular tone. The importance of endothelial cells and perivascular adipose tissue will be emphasised, as well as the role of capillaries. Finally the course will introduce arterial remodelling, how it occurs and the impact of remodelling on vascular function and health.
The students will be engaged in several lectures from international experts covering these topics, and also contribute by addressing some of the key vascular-related issues being discussed today. To do this, the students will be placed into groups of 4-5 persons ~3 weeks before the start of the meeting and given a topic (with related papers) to analyse, discuss and prepare a presentation. Half the group will present and argue for the pro argument and the other half will argue for the con arguments. The topics the students will be asked to debate on include:
– Will genome-wide association studies unlock the genetic basis of hypertension?
– Should there be a universal blood pressure goal of <130/80 mmHg?
– Is nighttime blood pressure important?
Teachers
Thomas Jepps
Associate Professor, Department of Biomedical Sciences, UCPH
Christian Aalkjær
Professor, Aarhus University
Manuel Navedo
Professor, University of California, Davis
Camilla Wenceslau
Professor, University of South Carolina
Mark Nelson
Professor, University of Vermont
Sophie Saxton
Senior Lecturer, University of Manchester
Ed van Bavel
Professor, University of Amsterdam
Course Location
Panum Institute
Blegdamsvej 3B
Copenhagen 2200